The aim of this thesis is to evaluate the benefits of the Ketogenic Diet (KD) for several medical conditions, in particular here are analized multiple sclerosis, epilepsy and cancer. The script is based on medical researches and trials published in the last few years, both on human and murine models, with the aim of investigating the possible advantages of KD as a medical aid to complement the standard treatment administred to patients. Human patients are given the restricted alimentar regimen based on the introduction of a low-carbohydrate intake in contrast with an high quantity of fats and proteins. After a couple of months, different examinations to evaluate several parameters of the pathology are taken in order to see if there are ameliorations. Despite the differences of some pathogenetic mechanisms, the complementary use of animal models, murine in particular, in the research is important to evaluate the role of the diet in the different medical conditions explored. At the end of the thesis,, relying on the results obtained, conclusions on the importance of the Ketogenic Diet for those medical conditions are drawn.
i benefici della dieta chetogenica in diverse patologie come sclerosi multipla, epilessia e cancro
CHIARAMELLO, MICOL
2021/2022
Abstract
The aim of this thesis is to evaluate the benefits of the Ketogenic Diet (KD) for several medical conditions, in particular here are analized multiple sclerosis, epilepsy and cancer. The script is based on medical researches and trials published in the last few years, both on human and murine models, with the aim of investigating the possible advantages of KD as a medical aid to complement the standard treatment administred to patients. Human patients are given the restricted alimentar regimen based on the introduction of a low-carbohydrate intake in contrast with an high quantity of fats and proteins. After a couple of months, different examinations to evaluate several parameters of the pathology are taken in order to see if there are ameliorations. Despite the differences of some pathogenetic mechanisms, the complementary use of animal models, murine in particular, in the research is important to evaluate the role of the diet in the different medical conditions explored. At the end of the thesis,, relying on the results obtained, conclusions on the importance of the Ketogenic Diet for those medical conditions are drawn.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.14240/86860