Trattamento superficiale della lega Ti45Nb ottimizzazione della morfologia e composizione superficiale per applicazioni di impianti biomedici.

The average age and life expectancy of humans continue to increase, leading to a growing demand for biomedical implant materials that is expected to further rise in the near future. This underscores the crucial importance of developing advanced and reliable implant materials to meet this increasing need. Over the past decade, research on biomaterials has highlighted the advantages of β-type tita-nium alloys over other types. β-type titanium alloys are valued for their higher biocompatibility, lower elastic modulus, and better resistance to controlled deformation and fatigue. In particular, the Ti45Nb alloy, incorporating non-toxic elements with a Young's modulus of approximately 62 GPa, has been recognized for its excellent biomechanical properties. In addition to mechanical and chemical characteristics, creating optimal surfaces is another crucial aspect for implant materials. These surfaces must promote bone cell growth and sup-port effective osseointegration with surrounding tissue. Therefore, various approaches have been developed to customize titanium-based implant surfaces using mechanical, chemical, or physical surface modification techniques. The goal is to create tailored surface topographies at the micro or nanoscale that further enhance the biofunctionality of implant surfaces, facilitating cell adhesion and proliferation. These advancements in biomaterial design aim not only to improve the performance of medi-cal implants but also to ensure greater durability and clinical success, significantly enhancing the quality of life for patients. In this thesis work, a β-type alloy was synthesized, in particular the Ti45Nb alloy. The aim of this thesis work is to modify the surface using a hydrothermal method in order to achieve a bioactive surface.